Griffith’s experiment Rough strain of Streptococcus was injected into the mouse. The mouse lived. Smooth strain of Streptococcus was injected into the mouse. The mouse died. When heat-killed smooth strain of Streptococcus was injected into the mouse, the mouse lived. In the last set of experiments, rough strain and heat-killed smooth strain were injected into the mouse. The mouse died. This …
Molecular Basis Of Inheritance – A good summary makes the whole chapter easy. 1 DNA, RNA and Search for Genetic Material The DNA DNA (Deoxyribonucleic acid) is a double-stranded, helical molecule. Its structure was cracked by Watson and Crick based on the X-ray crystallography results provided by Maurice Wilkins and Rosalind Franklin. Each strand of the DNA molecule is composed of …
Molecular Basis Of Inheritance – All formulas of the chapter at one glance. 1 Formula for Calculating the Length of DNA Total length of double helix DNA = Total number of base pairs x distance between two consecutive base pairs Example: 2 Formula for Chargaff’s rule It states that DNA from any cell of the organisms should …
Molecular Basis Of Inheritance – A concise set of notes for quick reference. 1 2 3 4
Lac operon
Mechanism of protein synthesis
Application of human genome project 1. Disorders: More than 1200 genes are responsible for common human cardiovascular diseases, endocrine diseases (like diabetes), neurological disorders (like Alzheimers disease), cancers and many more. 2. Cancers: Efforts are in progress to determine genes that will change cancerous cells to normal. 3. Health Care: It will indicate prospects for a healthier …
Reverse transcription 1. Reverse transcription is the synthesis of DNA from an RNA template. 2. A class of RNA viruses, called retroviruses, are characterized by the presence of an RNA-dependent DNA polymerase (reverse transcriptase). 3. For example, the virus that causes AIDS, is a retrovirus.
Wobble hypothesis 1. Wobble hypothesis explains the phenomena of multiple codons coding for the code for a single amino acid. 2. According to this theory the base in the first position of the anticodon on tRNA is an abnormal base which is able to pair with single type of nitrogenous bases in the third position of …
Characteristics of genetic code 1. Triplet code2. Start signal3. Stop signal4. Universal code5. Nonambiguous codons6. Related codons7. Commaless8. Polarity9. Degeneracy of code
